Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CKS1B | P61024 | 2/20 | 0.57 |
| ▸ | SKP1 | P63208 | 2/20 | 0.57 |
| ▸ | SKP2 | Q13309 | 2/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.49 |
| ▸ | MGLL | Q99685 | 1/20 | 0.49 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.49 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.48 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.47 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.47 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.47 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7981893 | 0.95 | GAA (0.56) | CKS1BSKP1SKP2GAASMN1; SMN2 | |
| SCHEMBL2465277 | 0.91 | NCF1 (0.56) | CKS1BSKP1SKP2GAASMN1; SMN2 | |
| SCHEMBL5338217 | 0.89 | CKS1B (0.50) | CKS1BSKP1SKP2GAASMN1; SMN2 | |
| SCHEMBL615074 | 0.86 | CHRM2 (0.52) | CKS1BSKP1SKP2GAASMN1; SMN2 | |
| SCHEMBL17276765 | 0.86 | CKS1B (0.55) | CKS1BSKP1SKP2GAASMN1; SMN2 | |
| SCHEMBL110163 | 0.85 | NCF1 (0.51) | CKS1BSKP1SKP2GAASMN1; SMN2 | |
| SCHEMBL5235727 | 0.85 | CKS1B (0.56) | CKS1BSKP1SKP2GAASMN1; SMN2 | |
| SCHEMBL5235579 | 0.85 | MEN1 (0.59) | CKS1BSKP1SKP2GAASMN1; SMN2 | |
| SCHEMBL30185679 | 0.85 | CKS1B (0.56) | CKS1BSKP1SKP2GAASMN1; SMN2 | |
| SCHEMBL28708137 | 0.85 | GPR119 (0.49) | CKS1BSKP1SKP2GAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6235731-B1 | REDUCING BLOOD LIPIDS, SUGARS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-05-22 | — | — | US | disclosed |