Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.41 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.38 |
| ▸ | NAMPT | P43490 | 2/20 | 0.38 |
| ▸ | FNTA | P49354 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7989631 | 1.00 | ALDH1A1 (0.45) | ALDH1A1KMT2AHDAC3HDAC4HDAC1 | |
| SCHEMBL7993721 | 0.88 | ALDH1A1 (0.40) | ALDH1A1KMT2AHDAC3HDAC4HDAC1 | |
| SCHEMBL7986078 | 0.79 | ALDH1A1 (0.46) | ALDH1A1KMT2AHDAC3HDAC4HDAC1 | |
| SCHEMBL7986075 | 0.79 | ALDH1A1 (0.46) | ALDH1A1KMT2AHDAC3HDAC4HDAC1 | |
| SCHEMBL7989744 | 0.76 | RECQL (0.45) | ALDH1A1KMT2AHDAC3HDAC4HDAC1 | |
| SCHEMBL7989742 | 0.76 | RECQL (0.45) | ALDH1A1KMT2AHDAC3HDAC4HDAC1 | |
| SCHEMBL7993715 | 0.73 | MMP2 (0.41) | ALDH1A1KMT2ARECQL | |
| SCHEMBL7989063 | 0.71 | EPHX2 (0.35) | ALDH1A1 | |
| SCHEMBL7975818 | 0.68 | CYP2D6 (0.35) | ALDH1A1LMNA | |
| SCHEMBL11329185 | 0.64 | CYP2A6 (0.59) | L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001040198-A2 | MACROCYCLIC HYDROXAMIC ACID DERIVATIVES AND THEIR USE AS ANTIMICROBIAL AGENTS | AVENTIS PHARMA S.A. (FR) | 2001-06-07 | — | — | WO | disclosed |