Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.34 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.33 |
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.32 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.32 |
| ▸ | CKS1B | P61024 | 1/20 | 0.32 |
| ▸ | SKP1 | P63208 | 1/20 | 0.32 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | AR | P10275 | 1/20 | 0.31 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.31 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7989777 | 0.99 | ADORA2A (0.34) | ADORA2ASCN5ASCN9AHTR4TPSAB1 | |
| SCHEMBL7983015 | 0.93 | TPSAB1 (0.38) | SCN5ASCN9AHTR4TPSAB1USP30 | |
| Hydrochloric Acid SCHEMBL7989389 | 0.92 | TPSAB1 (0.37) | SCN5ASCN9AHTR4TPSAB1USP30 | |
| SCHEMBL7971580 | 0.88 | KCNH2 (0.35) | HTR4RPS6KB1KCNH2CNR2 | |
| Hydrochloric Acid SCHEMBL7971809 | 0.87 | KCNH2 (0.35) | HTR4RPS6KB1KCNH2CNR2 | |
| SCHEMBL7983347 | 0.86 | CNR2 (0.34) | HTR4USP30CKS1BSKP1SKP2 | |
| Hydrochloric Acid SCHEMBL7985987 | 0.85 | CNR2 (0.34) | HTR4USP30CKS1BSKP1SKP2 | |
| SCHEMBL7989660 | 0.82 | USP30 (0.38) | SCN5AHTR4TPSAB1USP30CKS1B | |
| Hydrochloric Acid SCHEMBL7985995 | 0.82 | USP30 (0.38) | SCN5AHTR4TPSAB1USP30CKS1B | |
| SCHEMBL7982581 | 0.81 | CCR3 (0.46) | HTR4KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6235731-B1 | REDUCING BLOOD LIPIDS, SUGARS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-05-22 | — | — | US | disclosed |