Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 6/20 | 0.35 |
| ▸ | CACNA1I | Q9P0X4 | 2/20 | 0.35 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
| ▸ | FPR2 | P25090 | 1/20 | 0.34 |
| ▸ | TEAD1 | P28347 | 2/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.33 |
| ▸ | PIM1 | P11309 | 2/20 | 0.32 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7971809 | 0.99 | KCNH2 (0.35) | KCNH2CACNA1IMCHR1HTR1AADRA2A | |
| SCHEMBL7983015 | 0.88 | TPSAB1 (0.38) | HTR4 | |
| SCHEMBL7983347 | 0.88 | CNR2 (0.34) | CHRM4P2RX7HTR4PIM1CNR2 | |
| SCHEMBL7986094 | 0.88 | ADORA2A (0.34) | KCNH2HTR4RPS6KB1CNR2 | |
| Hydrochloric Acid SCHEMBL7989389 | 0.88 | TPSAB1 (0.37) | HTR4 | |
| Hydrochloric Acid SCHEMBL7985987 | 0.87 | CNR2 (0.34) | CHRM4P2RX7HTR4PIM1CNR2 | |
| Hydrochloric Acid SCHEMBL7989777 | 0.87 | ADORA2A (0.34) | KCNH2HTR4RPS6KB1CNR2 | |
| SCHEMBL7971581 | 0.82 | LMNA (0.42) | KCNH2CACNA1ICHRM4 | |
| Hydrochloric Acid SCHEMBL7971812 | 0.81 | LMNA (0.42) | KCNH2CACNA1ICHRM4 | |
| SCHEMBL7989660 | 0.80 | USP30 (0.38) | HTR4CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6235731-B1 | REDUCING BLOOD LIPIDS, SUGARS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-05-22 | — | — | US | disclosed |