Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 3/20 | 0.38 |
| ▸ | CKS1B | P61024 | 2/20 | 0.36 |
| ▸ | SKP1 | P63208 | 2/20 | 0.36 |
| ▸ | SKP2 | Q13309 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HTR4 | Q13639 | 2/20 | 0.35 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.35 |
| ▸ | CNR1 | P21554 | 3/20 | 0.35 |
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | SCN7A | Q01118 | 1/20 | 0.34 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.34 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7985995 | 0.99 | USP30 (0.38) | USP30CKS1BSKP1SKP2ALDH1A1 | |
| SCHEMBL7983015 | 0.90 | TPSAB1 (0.38) | USP30CKS1BSKP1SKP2HTR4 | |
| Hydrochloric Acid SCHEMBL7989389 | 0.89 | TPSAB1 (0.37) | USP30CKS1BSKP1SKP2HTR4 | |
| SCHEMBL7989618 | 0.88 | CCR5 (0.41) | USP30HTR4TPSAB1 | |
| Hydrochloric Acid SCHEMBL7972100 | 0.87 | CCR5 (0.41) | USP30HTR4TPSAB1 | |
| Hydrochloric Acid SCHEMBL7983228 | 0.84 | HDAC3 (0.50) | HTR4HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL7981833 | 0.83 | HTR4 (0.47) | HTR4HDAC3HDAC4HDAC1HDAC7 | |
| Hydrochloric Acid SCHEMBL7986403 | 0.82 | HTR4 (0.47) | HTR4HDAC3HDAC4HDAC1HDAC7 | |
| Hydrochloric Acid SCHEMBL7989777 | 0.82 | ADORA2A (0.34) | USP30CKS1BSKP1SKP2HTR4 | |
| SCHEMBL7989146 | 0.82 | HTR7 (0.49) | HTR4HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6235731-B1 | REDUCING BLOOD LIPIDS, SUGARS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-05-22 | — | — | US | disclosed |