Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALPL | P05186 | 1/20 | 0.67 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.41 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.39 |
| ▸ | MTOR | P42345 | 1/20 | 0.39 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.39 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.39 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.39 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9953892 | 0.90 | ALPL (0.60) | ALPLSLC22A12POLBPIK3CAMTOR | |
| SCHEMBL10288756 | 0.90 | ALPL (0.69) | ALPLPOLBMEN1KMT2APIK3CA | |
| SCHEMBL9954577 | 0.89 | ALPL (0.66) | ALPLSLC22A12KMT2APIK3CAPIK3CG | |
| SCHEMBL9955197 | 0.89 | ALPL (0.66) | ALPLSLC22A12POLBPIK3CAMTOR | |
| SCHEMBL798423 | 0.86 | ALPL (0.76) | ALPLKMT2APIK3CAPIK3CGPIK3CD | |
| SCHEMBL9954425 | 0.85 | ALPL (0.61) | ALPLSLC22A12POLBPIK3CAMTOR | |
| SCHEMBL10289041 | 0.84 | ALPL (0.62) | ALPLSLC22A12POLBPIK3CAMTOR | |
| SCHEMBL798326 | 0.83 | ALPL (0.69) | ALPLMEN1KMT2APIK3CAPIK3CG | |
| SCHEMBL798532 | 0.82 | ALPL (0.68) | ALPLMEN1MAPK1KMT2APIK3CA | |
| SCHEMBL9953673 | 0.82 | ALPL (0.65) | ALPLMAPK1KMT2APIK3CAPIK3CG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012174312-A2 | BENZIMIDAZOLE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-12-20 | — | — | WO | disclosed |
| WO-2012087938-A1 | QUINAZOLINONE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-06-28 | — | — | WO | disclosed |
| WO-2012037108-A1 | AMINOQUINOLINE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-03-22 | — | — | WO | disclosed |