Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALPL | P05186 | 1/20 | 0.66 |
| ▸ | BRD4 | O60885 | 3/20 | 0.42 |
| ▸ | BRD2 | P25440 | 2/20 | 0.42 |
| ▸ | BRD3 | Q15059 | 2/20 | 0.42 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.41 |
| ▸ | CCR4 | P51679 | 6/20 | 0.41 |
| ▸ | PIK3C3 | Q8NEB9 | 2/20 | 0.41 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.39 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.39 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10288756 | 0.89 | ALPL (0.69) | ALPLBRD4BRD2BRD3GRM4 | |
| SCHEMBL798611 | 0.89 | ALPL (0.67) | ALPLBRD4SMN1; SMN2SLC22A12ALDH1A1 | |
| SCHEMBL9955197 | 0.88 | ALPL (0.66) | ALPLPTGES2PIK3C3SMN1; SMN2SLC22A12 | |
| SCHEMBL798423 | 0.85 | ALPL (0.76) | ALPLLMNAALDH1A1KMT2APIK3CD | |
| SCHEMBL9954425 | 0.84 | ALPL (0.61) | ALPLPTGES2CCR4PIK3C3SMN1; SMN2 | |
| SCHEMBL9952780 | 0.83 | ALPL (0.68) | ALPLCCR4LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL9953892 | 0.83 | ALPL (0.60) | ALPLPTGES2PIK3C3SMN1; SMN2SLC22A12 | |
| SCHEMBL10289041 | 0.83 | ALPL (0.62) | ALPLPTGES2PIK3C3SMN1; SMN2SLC22A12 | |
| SCHEMBL9954845 | 0.83 | ALPL (0.67) | ALPLLMNASMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL9953673 | 0.81 | ALPL (0.65) | ALPLPTGES2CCR4PIK3C3SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012087938-A1 | QUINAZOLINONE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-06-28 | — | — | WO | disclosed |
| WO-2012087938-A1 | QUINAZOLINONE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-06-28 | — | — | WO | disclosed |