Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 12/20 | 0.39 |
| ▸ | STS | P08842 | 2/20 | 0.38 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | NAMPT | P43490 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7985595 | 1.00 | GPR119 (0.39) | GPR119STSPTPN2PTPN1PTPN6 | |
| SCHEMBL7983171 | 0.87 | FAAH (0.40) | GPR119NAMPT | |
| SCHEMBL7983168 | 0.87 | FAAH (0.40) | GPR119NAMPT | |
| SCHEMBL7989477 | 0.86 | KDM4E (0.47) | GPR119NAMPT | |
| SCHEMBL7989480 | 0.86 | KDM4E (0.47) | GPR119NAMPT | |
| SCHEMBL7973179 | 0.83 | GPR119 (0.39) | GPR119STS | |
| SCHEMBL7973184 | 0.83 | GPR119 (0.39) | GPR119STS | |
| SCHEMBL7987858 | 0.81 | TGFBR1 (0.44) | — | |
| SCHEMBL7987855 | 0.81 | TGFBR1 (0.44) | — | |
| Hydrochloric Acid SCHEMBL7971644 | 0.80 | IRAK4 (0.30) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6235731-B1 | REDUCING BLOOD LIPIDS, SUGARS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-05-22 | — | — | US | disclosed |
| EP-0915888-A1 | FUSED IMIDAZOPYRIDINE DERIVATIVES AS ANTIHYPERLIPIDEMIC AGENTS | Takeda Chemical Industries, Ltd. (JP) | 1999-05-19 | — | — | EP | disclosed |
| WO-1997040051-A1 | FUSED IMIDAZOPYRIDINE DERIVATIVES AS ANTIHYPERLIPIDEMIC AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-10-30 | — | — | WO | disclosed |