Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 2/20 | 0.57 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.57 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.57 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.57 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.57 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.57 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.57 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.57 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.57 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.57 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.57 |
| ▸ | PIN1 | Q13526 | 6/20 | 0.54 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.53 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.53 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.53 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | TMIGD3 | P0DMS9 | 1/20 | 0.47 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.47 |
| ▸ | STAT1 | P42224 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7998294 | 0.89 | HDAC3 (0.57) | HDAC1HDAC3HDAC4HDAC7HDAC2 | |
| SCHEMBL13753491 | 0.80 | HDAC3 (0.64) | HDAC1HDAC3HDAC4HDAC7HDAC2 | |
| SCHEMBL13753385 | 0.80 | HDAC3 (0.68) | HDAC1HDAC3HDAC4HDAC7HDAC2 | |
| SCHEMBL38664814 | 0.78 | HDAC1 (0.74) | HDAC1HDAC3HDAC4HDAC7HDAC2 | |
| SCHEMBL741039 | 0.78 | HDAC1 (0.74) | HDAC1HDAC3HDAC4HDAC7HDAC2 | |
| SCHEMBL3078403 | 0.76 | TAS1R3 (0.78) | HDAC1HDAC3HDAC4HDAC7HDAC2 | |
| SCHEMBL704949 | 0.76 | TAS1R3 (0.78) | HDAC1HDAC3HDAC4HDAC7HDAC2 | |
| SCHEMBL4619875 | 0.75 | TAS1R3 (0.62) | HDAC1HDAC3HDAC4HDAC7HDAC2 | |
| SCHEMBL17991867 | 0.75 | PIN1 (0.65) | HDAC1HDAC3HDAC4HDAC7HDAC2 | |
| SCHEMBL11296987 | 0.75 | PIN1 (0.65) | HDAC1HDAC3HDAC4HDAC7HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009146182-A1 | TRPV4 ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 2009-12-03 | — | — | WO | disclosed |