Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.44 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 4/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
| ▸ | CES1 | P23141 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 4/20 | 0.41 |
| ▸ | CA2 | P00918 | 4/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.40 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.40 |
| ▸ | PARP4 | Q9UKK3 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7084895 | 0.82 | MAPT (0.48) | MAPTCYP1A2CYP1A1CYP1B1ALDH1A1 | |
| SCHEMBL5265061 | 0.81 | CYP1A2 (0.51) | MAPTCYP1A2CYP1A1CYP1B1ALDH1A1 | |
| SCHEMBL5215589 | 0.81 | CES2 (0.57) | MAPTCYP1A2ALDH1A1NPC1RAB9A | |
| SCHEMBL7985890 | 0.79 | AKR1C3 (0.50) | MAPTCYP1A2ALDH1A1NPC1RAB9A | |
| SCHEMBL1875492 | 0.78 | RAB9A (0.53) | MAPTALDH1A1NPC1RAB9APAX8 | |
| SCHEMBL7089298 | 0.76 | CES2 (0.73) | MAPTCYP1A2CYP1A1CYP1B1ALDH1A1 | |
| SCHEMBL8392486 | 0.76 | MAPT (0.61) | MAPTCYP1A2CYP1A1CYP1B1ALDH1A1 | |
| SCHEMBL17290923 | 0.75 | ALDH1A1 (0.45) | MAPTALDH1A1NPC1RAB9AKMT2A | |
| SCHEMBL15665536 | 0.75 | CA1 (0.52) | MAPTCYP1A2ALDH1A1NPC1RAB9A | |
| SCHEMBL5217880 | 0.73 | MAPT (0.63) | MAPTCYP1A2ALDH1A1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6294568-B1 | ANTIINFLAMMATORY AGENTS AND ANTITUMOR AGENTS CONTAINING THE COMPOUNDS AS THE ACTIVE INGREDIENTS AND COX2 ENZYME INHIBITORS | NISSIN FOOD PRODUCTS CO., LTD. (JP) | 2001-09-25 | — | — | US | disclosed |
| EP-1048649-A1 | 5-ARYLPYRROLE DERIVATIVES | NISSIN FOOD PRODUCTS CO., LTD. (JP) | 2000-11-02 | — | — | EP | disclosed |