Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.53 |
| ▸ | CA2 | P00918 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | FYN | P06241 | 1/20 | 0.46 |
| ▸ | TUBB4A | P04350 | 4/20 | 0.45 |
| ▸ | TUBB | P07437 | 4/20 | 0.45 |
| ▸ | TUBA3C | P0DPH7 | 4/20 | 0.45 |
| ▸ | TUBA1B | P68363 | 4/20 | 0.45 |
| ▸ | TUBA4A | P68366 | 4/20 | 0.45 |
| ▸ | TUBB4B | P68371 | 4/20 | 0.45 |
| ▸ | TUBB3 | Q13509 | 4/20 | 0.45 |
| ▸ | TUBB2A | Q13885 | 4/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19668723 | 0.75 | MAPT (0.47) | CA1CA2ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL28233679 | 0.73 | MAPT (0.56) | CA1CA2KDM4EMEN1ALDH1A1 | |
| SCHEMBL3435546 | 0.72 | MAPT (0.47) | CA1CA2KDM4EMEN1ALDH1A1 | |
| SCHEMBL18492964 | 0.72 | HDAC8 (0.58) | KDM4EMEN1ALDH1A1HPGDMAPK1 | |
| SCHEMBL2765741 | 0.72 | CA1 (0.40) | CA1CA2KDM4EALDH1A1HPGD | |
| SCHEMBL2764186 | 0.72 | FYN (0.40) | CA1CA2KDM4EALDH1A1HPGD | |
| SCHEMBL11077809 | 0.71 | MAPT (0.54) | CA1CA2MEN1ALDH1A1MAPK1 | |
| SCHEMBL6693299 | 0.71 | ATM (0.55) | KDM4EMEN1ALDH1A1HPGDMAPK1 | |
| SCHEMBL2448859 | 0.71 | KIT (0.58) | KDM4EMEN1ALDH1A1HPGDMAPK1 | |
| SCHEMBL28234703 | 0.70 | KDM4E (0.47) | KDM4EMEN1ALDH1A1HPGDMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010000372-A2 | NEW DRUG FOR INHIBITING AGGREGATION OF PROTEINS INVOLVED IN DISEASES LINKED TO PROTEIN AGGREGATION AND/OR NEURODEGENERATIVE DISEASES | LUDWIG-MAXIMILIANS-UNIVERSITÄT MÜNCHEN (DE) | 2010-01-07 | — | — | WO | disclosed |