Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNOT7 | Q9UIV1 | 6/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.40 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | DHPS | P49366 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CLK1 | P49759 | 1/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.39 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7974048 | 0.94 | CNOT7 (0.53) | CNOT7HPGDALDH1A1ADRA2CCYP2E1 | |
| SCHEMBL7974620 | 0.90 | CNOT7 (0.58) | CNOT7ALDH1A1TSHR | |
| SCHEMBL7974289 | 0.89 | CNOT7 (0.53) | CNOT7HPGDALDH1A1CYP2E1CYP3A4 | |
| SCHEMBL7991681 | 0.88 | CNOT7 (0.54) | CNOT7HPGDALDH1A1MAPT | |
| SCHEMBL7984244 | 0.83 | CNOT7 (0.60) | CNOT7ALDH1A1TSHRMAPTRAB9A | |
| SCHEMBL7986324 | 0.83 | HPGD (0.48) | CNOT7HPGDALDH1A1CYP2E1CYP3A4 | |
| SCHEMBL7973875 | 0.83 | CNOT7 (0.53) | CNOT7ALDH1A1TSHR | |
| SCHEMBL7988553 | 0.82 | CNOT7 (0.50) | CNOT7ALDH1A1 | |
| SCHEMBL7984686 | 0.82 | CNOT7 (0.50) | CNOT7ALDH1A1 | |
| SCHEMBL7984409 | 0.82 | CNOT7 (0.53) | CNOT7ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |