Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNOT7 | Q9UIV1 | 9/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | TNKS | O95271 | 1/20 | 0.41 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.41 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | PARN | O95453 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | CASP1 | P29466 | 2/20 | 0.39 |
| ▸ | CASP7 | P55210 | 2/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7985605 | 0.94 | CNOT7 (0.54) | CNOT7ALDH1A1TNKSTNKS2PARP2 | |
| SCHEMBL7974620 | 0.92 | CNOT7 (0.58) | CNOT7ALDH1A1LMNAMAPK1KDM4E | |
| SCHEMBL7974508 | 0.89 | CNOT7 (0.51) | CNOT7ALDH1A1TNKSTNKS2PARP2 | |
| SCHEMBL7984686 | 0.88 | CNOT7 (0.50) | CNOT7ALDH1A1LMNAMAPK1KDM4E | |
| SCHEMBL7991681 | 0.88 | CNOT7 (0.54) | CNOT7ALDH1A1LMNAMAPK1KDM4E | |
| SCHEMBL7984244 | 0.85 | CNOT7 (0.60) | CNOT7ALDH1A1LMNAMAPK1KDM4E | |
| SCHEMBL7974278 | 0.84 | CNOT7 (0.53) | CNOT7ALDH1A1LMNAMAPK1KDM4E | |
| SCHEMBL7986522 | 0.84 | CNOT7 (0.48) | CNOT7ALDH1A1TNKSTNKS2PARP2 | |
| SCHEMBL7986330 | 0.83 | CNOT7 (0.51) | CNOT7ALDH1A1TSHR | |
| SCHEMBL7984493 | 0.83 | CNOT7 (0.54) | CNOT7ALDH1A1TNKSTNKS2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |