Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNOT7 | Q9UIV1 | 10/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | GSK3B | P49841 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | PARN | O95453 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.40 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7991656 | 0.93 | CNOT7 (0.55) | CNOT7ALDH1A1GSK3BKDM4ELMNA | |
| SCHEMBL7974620 | 0.93 | CNOT7 (0.58) | CNOT7ALDH1A1KDM4ELMNAPOLB | |
| SCHEMBL7974444 | 0.88 | CNOT7 (0.52) | CNOT7ALDH1A1GSK3BKDM4EPARN | |
| SCHEMBL7986330 | 0.88 | CNOT7 (0.51) | CNOT7ALDH1A1MAPTHPGD | |
| SCHEMBL7973875 | 0.88 | CNOT7 (0.53) | CNOT7ALDH1A1KDM4ELMNAPOLB | |
| SCHEMBL7984244 | 0.86 | CNOT7 (0.60) | CNOT7ALDH1A1KDM4ELMNAPOLB | |
| SCHEMBL7985291 | 0.84 | CNOT7 (0.54) | CNOT7ALDH1A1KDM4ELMNAPOLB | |
| SCHEMBL7984686 | 0.83 | CNOT7 (0.50) | CNOT7ALDH1A1KDM4ELMNAPOLB | |
| SCHEMBL7984409 | 0.83 | CNOT7 (0.53) | CNOT7ALDH1A1KDM4ELMNAPOLB | |
| SCHEMBL7988553 | 0.83 | CNOT7 (0.50) | CNOT7ALDH1A1PARNCXCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |