Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 6/20 | 0.43 |
| ▸ | HTR4 | Q13639 | 2/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
| ▸ | AURKA | O14965 | 1/20 | 0.36 |
| ▸ | F10 | P00742 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7982153 | 0.99 | HTR7 (0.43) | HTR7HTR4KCNH2MCHR1HTR2A | |
| SCHEMBL7986166 | 0.93 | HTR4 (0.42) | HTR7HTR4KCNH2MEN1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL7971705 | 0.92 | HTR4 (0.41) | HTR7HTR4KCNH2MEN1ALDH1A1 | |
| SCHEMBL7982288 | 0.89 | HTR7 (0.44) | HTR7HTR4KCNH2HTR2AKDM1A | |
| SCHEMBL7985386 | 0.89 | HTR4 (0.42) | HTR7HTR4HTR2AKDM1A | |
| SCHEMBL7971626 | 0.89 | HTR7 (0.44) | HTR7KCNH2KDM1AGSK3B | |
| Hydrochloric Acid SCHEMBL7985643 | 0.89 | HTR7 (0.44) | HTR7HTR4KCNH2HTR2AKDM1A | |
| SCHEMBL7983128 | 0.89 | HTR2A (0.40) | HTR7HTR4KCNH2HTR2AMEN1 | |
| Hydrochloric Acid SCHEMBL7986100 | 0.89 | HTR7 (0.44) | HTR7KCNH2KDM1AGSK3B | |
| Hydrochloric Acid SCHEMBL7972092 | 0.89 | HTR4 (0.42) | HTR7HTR4HTR2AKDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6235731-B1 | REDUCING BLOOD LIPIDS, SUGARS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-05-22 | — | — | US | disclosed |
| EP-0915888-A1 | FUSED IMIDAZOPYRIDINE DERIVATIVES AS ANTIHYPERLIPIDEMIC AGENTS | Takeda Chemical Industries, Ltd. (JP) | 1999-05-19 | — | — | EP | disclosed |
| WO-1997040051-A1 | FUSED IMIDAZOPYRIDINE DERIVATIVES AS ANTIHYPERLIPIDEMIC AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-10-30 | — | — | WO | disclosed |