Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 7/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.54 |
| ▸ | MEN1 | O00255 | 4/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | HTT | P42858 | 3/20 | 0.54 |
| ▸ | TSHR | P16473 | 5/20 | 0.53 |
| ▸ | GAA | P10253 | 4/20 | 0.53 |
| ▸ | USP2 | O75604 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | CASP1 | P29466 | 1/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4522517 | 0.84 | HRH3 (0.51) | ALDH1A1TSHRGAA | |
| SCHEMBL8124622 | 0.72 | TSHR (0.68) | ALDH1A1NPSR1KDM4EMEN1KMT2A | |
| SCHEMBL8134516 | 0.72 | TSHR (0.57) | ALDH1A1NPSR1KDM4EMEN1KMT2A | |
| SCHEMBL5908646 | 0.71 | USP2 (0.52) | ALDH1A1NPSR1KDM4EMEN1KMT2A | |
| SCHEMBL4132569 | 0.71 | ALDH1A1 (0.53) | ALDH1A1KDM4EHTTTSHRGAA | |
| SCHEMBL7150528 | 0.70 | ALDH1A1 (0.56) | ALDH1A1NPSR1KDM4EMEN1KMT2A | |
| SCHEMBL27475533 | 0.70 | HSD17B10 (0.55) | ALDH1A1NPSR1KDM4EMEN1KMT2A | |
| SCHEMBL5806082 | 0.70 | AKR1C3 (0.50) | ALDH1A1NPSR1KDM4EMEN1KMT2A | |
| SCHEMBL7684043 | 0.70 | ALDH1A1 (0.54) | ALDH1A1NPSR1KDM4EHTTTSHR | |
| SCHEMBL19732308 | 0.70 | ALDH1A1 (0.54) | ALDH1A1KDM4EMEN1KMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6265434-B1 | ANTIINFLAMMATORY AGENTS | MERCK & CO., INC. | 2001-07-24 | — | — | US | disclosed |