Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 4/20 | 0.50 |
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.49 |
| ▸ | FEN1 | P39748 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | CMA1 | P23946 | 1/20 | 0.46 |
| ▸ | TOP2A | P11388 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28210571 | 0.85 | LMNA (0.57) | ALDH1A1TSHRPOLBHTTLMNA | |
| SCHEMBL1768224 | 0.83 | ALDH1A1 (0.54) | ALDH1A1PKMGAATSHRALOX15 | |
| SCHEMBL19732308 | 0.83 | ALDH1A1 (0.54) | ALDH1A1PKMGAATSHRALOX15 | |
| Hydrochloric Acid SCHEMBL27925071 | 0.83 | LMNA (0.55) | ALDH1A1GAATSHRPOLBHTT | |
| SCHEMBL7433479 | 0.82 | ALDH1A1 (0.53) | ALDH1A1PKMGAATSHRALOX15 | |
| SCHEMBL4132569 | 0.82 | ALDH1A1 (0.53) | ALDH1A1PKMGAATSHRALOX15 | |
| SCHEMBL4631721 | 0.82 | ALDH1A1 (0.53) | ALDH1A1PKMGAATSHRALOX15 | |
| SCHEMBL7148471 | 0.81 | ALDH1A1 (0.62) | ALDH1A1PKMGAATSHRALOX15 | |
| SCHEMBL19726570 | 0.80 | ALDH1A1 (0.51) | ALDH1A1PKMGAATSHRALOX15 | |
| SCHEMBL1768222 | 0.80 | ALDH1A1 (0.51) | ALDH1A1PKMGAATSHRALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1910151-A | Cyclic amine derivative with heteroaryl ring | SANKYO CO (JP) | 2007-02-07 | — | — | CN | disclosed |
| US-6376484-B1 | FOR PREVENTION AND/OR TREATMENT OF VARIOUS KINDS OF INFLAMMATORY DISEASE | ONO PHARMACEUTICAL CO., LTD. (JP) | 2002-04-23 | — | — | US | disclosed |
| US-6136834-A | TETRAZOLE PEPTIDES | ONO PHARMACEUTICAL CO., LTD. (JP) | 2000-10-24 | — | — | US | disclosed |
| EP-0900791-A1 | TETRAZOLE DERIVATIVES AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO., LTD. (JP) | 1999-03-10 | — | — | EP | disclosed |