Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.54 |
| ▸ | F2 | P00734 | 1/20 | 0.51 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17863558 | 0.95 | KDM4E (0.54) | KDM4EHRH3MEN1KMT2ANPSR1 | |
| SCHEMBL5800630 | 0.88 | KDM4E (0.69) | KDM4EHRH3MEN1KMT2ANPSR1 | |
| SCHEMBL17863572 | 0.85 | KDM4E (0.49) | KDM4EHRH3MEN1KMT2AF2 | |
| SCHEMBL17346763 | 0.85 | NOS3 (0.56) | KDM4EMEN1KMT2ANPSR1SMN1; SMN2 | |
| SCHEMBL4197501 | 0.84 | KDM4E (0.69) | KDM4EHRH3MEN1KMT2ANPSR1 | |
| SCHEMBL6559744 | 0.83 | KDM4E (0.68) | KDM4EHRH3MEN1KMT2ANPSR1 | |
| SCHEMBL5217325 | 0.83 | KDM4E (0.68) | KDM4EHRH3MEN1KMT2ANPSR1 | |
| SCHEMBL17864835 | 0.81 | KDM4E (0.51) | KDM4EHRH3MEN1KMT2ANPSR1 | |
| SCHEMBL4560494 | 0.81 | HRH3 (0.72) | HRH3MEN1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL17863574 | 0.80 | PRSS1 (0.47) | KDM4EHRH3MEN1KMT2ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6191146-B1 | BACTERICIDES, FUNGICIDES, VIRICIDES | SMITHKLINE BEECHAM CORPORATION | 2001-02-20 | — | — | US | disclosed |