Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EDNRA | P25101 | 6/20 | 0.54 |
| ▸ | SIRT2 | Q8IXJ6 | 13/20 | 0.51 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7990492 | 0.92 | SIRT2 (0.44) | EDNRASIRT2 | |
| SCHEMBL7990137 | 0.90 | MAPK9 (0.46) | EDNRASIRT2 | |
| SCHEMBL7990231 | 0.77 | NMBR (0.54) | — | |
| SCHEMBL2000374 | 0.76 | SIRT2 (0.61) | SIRT2 | |
| SCHEMBL22356512 | 0.76 | SIRT2 (0.61) | SIRT2 | |
| SCHEMBL1999739 | 0.75 | SIRT2 (0.60) | SIRT2 | |
| SCHEMBL522051 | 0.75 | SIRT2 (0.60) | SIRT2 | |
| SCHEMBL10026712 | 0.75 | SIRT2 (0.60) | SIRT2 | |
| SCHEMBL523065 | 0.75 | SIRT2 (0.60) | SIRT2 | |
| Hydrochloric Acid SCHEMBL522050 | 0.74 | SIRT2 (0.59) | SIRT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6207686-B1 | FOR THERAPY OF HYPERTENSION | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-03-27 | — | — | US | disclosed |
| EP-0792265-A1 | ENDOTHELIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-09-03 | — | — | EP | disclosed |
| WO-1996015109-A1 | ENDOTHELIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-05-23 | — | — | WO | disclosed |