Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 13/20 | 0.38 |
| ▸ | ITGA2B | P08514 | 13/20 | 0.38 |
| ▸ | NOD1 | Q9Y239 | 4/20 | 0.34 |
| ▸ | FAAH | O00519 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8492244 | 1.00 | ITGB3 (0.38) | ITGB3ITGA2BNOD1FAAHALDH1A1 | |
| SCHEMBL8492251 | 0.86 | FAAH (0.34) | ITGB3ITGA2BNOD1FAAHALDH1A1 | |
| SCHEMBL7439854 | 0.86 | FAAH (0.34) | ITGB3ITGA2BNOD1FAAHALDH1A1 | |
| SCHEMBL7982793 | 0.85 | ITGB3 (0.43) | ITGB3ITGA2B | |
| SCHEMBL7969566 | 0.85 | ITGB3 (0.44) | ITGB3ITGA2BNOD1FAAH | |
| SCHEMBL7439842 | 0.80 | ITGB3 (0.39) | ITGB3ITGA2B | |
| SCHEMBL7986508 | 0.80 | ITGB3 (0.39) | ITGB3ITGA2B | |
| SCHEMBL7450458 | 0.70 | CRHBP (0.35) | ITGB3ITGA2BNOD1FAAHALDH1A1 | |
| SCHEMBL7969570 | 0.69 | ITGB3 (0.56) | ITGB3ITGA2B | |
| SCHEMBL7450451 | 0.69 | ITGB3 (0.56) | ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6191282-B1 | DERIVATIVES OF 5-MEMBERED NITROGEN CONTAINING HETEROCYCLIC RING IS USED AS ANTICARCINOGENIC AGENT AND ANTICOAGULANT | HOECHST MARION ROUSSEL (DE) | 2001-02-20 | — | — | US | disclosed |
| US-5981492-A | ADMINISTERED TO THE PATIENT TO INHIBIT THROMBOCYTE AGGREGATION, THE METASTASIZATION OF CARCINOMA CELLS, THE BINDING OF OSTEOCLASTS TO THE BONE SURFACE, OR FOR THE TREATMENT OF THROMBOSES | HOECHST AKTIENGESELLSCHAFT (DE) | 1999-11-09 | — | — | US | disclosed |