Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 5/20 | 0.44 |
| ▸ | DRD2 | P14416 | 3/20 | 0.44 |
| ▸ | DRD3 | P35462 | 3/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | MC4R | P32245 | 1/20 | 0.39 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7986159 | 0.86 | DHFR (0.42) | DRD4DRD2DRD3MAPTSIGMAR1 | |
| SCHEMBL27468194 | 0.80 | TNKS2 (0.46) | MAPTALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL7986532 | 0.78 | TSHR (0.46) | DRD4DRD2DRD3NPSR1L3MBTL1 | |
| SCHEMBL6200943 | 0.77 | OPRM1 (0.40) | ALDH1A1 | |
| SCHEMBL7983801 | 0.76 | ALDH1A1 (0.42) | L3MBTL1ALDH1A1MEN1KMT2AHTT | |
| SCHEMBL29614674 | 0.73 | PARP1 (0.43) | L3MBTL1MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL4910773 | 0.72 | WEE1 (0.38) | MAPTALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL6644399 | 0.72 | HTR7 (0.37) | DRD2DRD3ALDH1A1 | |
| SCHEMBL7986389 | 0.71 | CCR3 (0.50) | ALDH1A1KMT2ASIGMAR1 | |
| SCHEMBL7986525 | 0.70 | CCR3 (0.56) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6235731-B1 | REDUCING BLOOD LIPIDS, SUGARS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-05-22 | — | — | US | disclosed |