Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR5 | P51681 | 1/20 | 0.40 |
| ▸ | EP300 | Q09472 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
| ▸ | SCN1A | P35498 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.36 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7494679 | 1.00 | CCR5 (0.40) | CCR5EP300SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL7494676 | 1.00 | CCR5 (0.40) | CCR5EP300SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL5762162 | 0.79 | SLC6A4 (0.43) | SLC6A4SLC6A3SLC6A2HTR2CCHRM2 | |
| Hydrochloric Acid SCHEMBL7662119 | 0.78 | HTR2C (0.44) | SLC6A4SLC6A3SLC6A2HTR2CCHRM2 | |
| SCHEMBL7436672 | 0.78 | SLC6A4 (0.39) | SLC6A4HTR2CMEN1LMNACYP2D6 | |
| SCHEMBL6608292 | 0.76 | MEN1 (0.50) | SLC6A4SLC6A3SLC6A2HTR2CMEN1 | |
| SCHEMBL12712581 | 0.72 | TNKS (0.40) | SLC6A4SLC6A3MEN1LMNACYP2D6 | |
| SCHEMBL907558 | 0.72 | TNKS (0.40) | SLC6A4SLC6A3MEN1LMNACYP2D6 | |
| SCHEMBL8307801 | 0.71 | MAOB (0.53) | SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL2306732 | 0.71 | MEN1 (0.68) | SLC6A4SLC6A3SLC6A2HTR2CMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6265434-B1 | ANTIINFLAMMATORY AGENTS | MERCK & CO., INC. | 2001-07-24 | — | — | US | disclosed |