Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMYD2 | Q9NRG4 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.40 |
| ▸ | FPR3 | P25089 | 1/20 | 0.40 |
| ▸ | FPR2 | P25090 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7971940 | 0.99 | SMYD2 (0.41) | SMYD2ALDH1A1CYP2D6SMAD3FPR3 | |
| SCHEMBL7985583 | 0.97 | ALDH1A1 (0.43) | SMYD2ALDH1A1NPC1HTTRAB9A | |
| SCHEMBL7984736 | 0.97 | SMYD2 (0.46) | SMYD2ALDH1A1CYP2D6SMAD3FPR3 | |
| Hydrochloric Acid SCHEMBL7983892 | 0.96 | ALDH1A1 (0.42) | SMYD2ALDH1A1NPC1HTTRAB9A | |
| Hydrochloric Acid SCHEMBL7981574 | 0.96 | SMYD2 (0.45) | SMYD2ALDH1A1CYP2D6SMAD3FPR3 | |
| SCHEMBL7972040 | 0.94 | SIGMAR1 (0.40) | ALDH1A1NPC1HTTRAB9ASMN1; SMN2 | |
| SCHEMBL7984706 | 0.93 | DRD3 (0.42) | ALDH1A1CYP2D6SMN1; SMN2KDM4EGFER | |
| Hydrochloric Acid SCHEMBL7982606 | 0.93 | FAAH (0.39) | ALDH1A1NPC1HTTRAB9ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL7982703 | 0.92 | DRD3 (0.42) | ALDH1A1CYP2D6SMN1; SMN2KDM4EGFER | |
| SCHEMBL7986609 | 0.90 | DRD3 (0.44) | ALDH1A1CYP2D6SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6235731-B1 | REDUCING BLOOD LIPIDS, SUGARS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-05-22 | — | — | US | disclosed |
| EP-0915888-A1 | FUSED IMIDAZOPYRIDINE DERIVATIVES AS ANTIHYPERLIPIDEMIC AGENTS | Takeda Chemical Industries, Ltd. (JP) | 1999-05-19 | — | — | EP | disclosed |
| WO-1997040051-A1 | FUSED IMIDAZOPYRIDINE DERIVATIVES AS ANTIHYPERLIPIDEMIC AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-10-30 | — | — | WO | disclosed |