Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 2/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | POLQ | O75417 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.36 |
| ▸ | RORC | P51449 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | ESRRG | P62508 | 1/20 | 0.32 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.32 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9229560 | 0.81 | ESR1 (0.46) | HDAC6ESR1ACHEOPRM1OPRL1 | |
| SCHEMBL5542515 | 0.80 | ESR1 (0.39) | HDAC6ESR1ACHEPOLQCNR2 | |
| SCHEMBL5539629 | 0.76 | ESR1 (0.40) | HDAC6ESR1ACHEPOLQCNR2 | |
| SCHEMBL24202152 | 0.73 | OPRM1 (0.39) | ACHEOPRM1OPRL1BCHEPDK2 | |
| SCHEMBL25909572 | 0.73 | TRPV1 (0.41) | OPRM1OPRL1 | |
| SCHEMBL6550713 | 0.72 | ESR1 (0.44) | HDAC6ESR1ACHEBCHESLC6A2 | |
| SCHEMBL4089138 | 0.72 | MLYCD (0.42) | OPRM1OPRL1SIGMAR1ESRRG | |
| SCHEMBL9436565 | 0.72 | OPRM1 (0.46) | OPRM1OPRL1BCHESIGMAR1 | |
| SCHEMBL3038423 | 0.72 | OPRM1 (0.46) | OPRM1OPRL1BCHESIGMAR1 | |
| SCHEMBL5539229 | 0.72 | ESR1 (0.39) | HDAC6ESR1POLQCNR2RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6214833-B1 | MADE BY ACYLATION | ZAMBON GROUP S.P.A. (IT) | 2001-04-10 | — | — | US | disclosed |
| EP-0970075-A1 | PYRIMIDINONE-1,3-OXATHIOLANE DERIVATIVES WITH ANTIVIRAL ACTIVITY | ZAMBON GROUP S.p.A. (IT) | 2000-01-12 | — | — | EP | disclosed |
| WO-1998043972-A1 | PYRIMIDINONE-1,3-OXATHIOLANE DERIVATIVES WITH ANTIVIRAL ACTIVITY | ZAMBON GROUP S.P.A. (IT) | 1998-10-08 | — | — | WO | disclosed |