Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 4/20 | 0.45 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 3/20 | 0.38 |
| ▸ | ACHE | P22303 | 3/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | KDM4A | O75164 | 6/20 | 0.36 |
| ▸ | KDM4C | Q9H3R0 | 6/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | KDM5A | P29375 | 1/20 | 0.35 |
| ▸ | KDM7A | Q6ZMT4 | 1/20 | 0.35 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.35 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7986215 | 0.90 | EPHX2 (0.38) | EPHX2ABCC4MAPTALDH1A1LMNA | |
| SCHEMBL16802992 | 0.81 | EPHX2 (0.54) | EPHX2ABCC4MAPTALDH1A1LMNA | |
| SCHEMBL7986950 | 0.81 | EPHX2 (0.39) | EPHX2ABCC4MAPTALDH1A1LMNA | |
| SCHEMBL21461989 | 0.80 | CNR1 (0.43) | EPHX2BCHEACHECHRM2KDM4A | |
| SCHEMBL20536032 | 0.79 | EPHX2 (0.56) | EPHX2KDM4AKDM4CKDM5APHF8 | |
| SCHEMBL3168992 | 0.78 | ALDH1A1 (0.47) | EPHX2ABCC4MAPTALDH1A1LMNA | |
| SCHEMBL1469535 | 0.78 | MAPT (0.54) | EPHX2ABCC4MAPTALDH1A1LMNA | |
| SCHEMBL30449957 | 0.78 | MAPT (0.54) | EPHX2ABCC4MAPTALDH1A1LMNA | |
| SCHEMBL4021318 | 0.78 | MAPT (0.54) | EPHX2ABCC4MAPTALDH1A1LMNA | |
| SCHEMBL23065435 | 0.77 | EPHX2 (0.61) | EPHX2ABCC4MAPTALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001040198-A2 | MACROCYCLIC HYDROXAMIC ACID DERIVATIVES AND THEIR USE AS ANTIMICROBIAL AGENTS | AVENTIS PHARMA S.A. (FR) | 2001-06-07 | — | — | WO | disclosed |