Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 6/20 | 0.39 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | Q9HBH1 | 1/20 | 0.33 | |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 3/20 | 0.32 |
| ▸ | KDM4A | O75164 | 2/20 | 0.32 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.32 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.32 |
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7989540 | 0.92 | PDF (0.34) | EPHX2ABCC4MAPTPDF | |
| SCHEMBL7987318 | 0.84 | PDF (0.33) | ||
| SCHEMBL7976171 | 0.81 | PDF (0.33) | ||
| SCHEMBL7987073 | 0.81 | EPHX2 (0.45) | EPHX2ABCC4MAPTALDH1A1LMNA | |
| SCHEMBL7990027 | 0.80 | PDF (0.35) | ||
| SCHEMBL7987210 | 0.78 | PDF (0.33) | EPHX2ABCC4MAPTPDF | |
| SCHEMBL7986860 | 0.75 | MMP2 (0.38) | KDM4A | |
| SCHEMBL7989538 | 0.74 | PDF (0.43) | ||
| SCHEMBL7976169 | 0.73 | PDF (0.44) | ||
| SCHEMBL7977102 | 0.73 | PDF (0.44) |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001040198-A2 | MACROCYCLIC HYDROXAMIC ACID DERIVATIVES AND THEIR USE AS ANTIMICROBIAL AGENTS | AVENTIS PHARMA S.A. (FR) | 2001-06-07 | — | — | WO | disclosed |