Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.48 |
| ▸ | NAMPT | P43490 | 1/20 | 0.46 |
| ▸ | DHODH | Q02127 | 1/20 | 0.42 |
| ▸ | ITGB3 | P05106 | 4/20 | 0.41 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.39 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | SCN1A | P35498 | 1/20 | 0.39 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.39 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21180879 | 0.80 | ALDH1A1 (0.57) | LMNAALDH1A1HIF1ATSHRSCN1A | |
| SCHEMBL7984274 | 0.78 | KDM4E (0.53) | — | |
| SCHEMBL11539374 | 0.77 | SLC6A4 (0.53) | SLC6A4SLC6A2 | |
| SCHEMBL27265378 | 0.77 | SLC6A4 (0.42) | SLC6A4NAMPTITGB3ITGA2BSLC6A3 | |
| SCHEMBL7987096 | 0.76 | CYP4A11 (0.56) | ALDH1A1ITGB3ITGA2BHIF1A | |
| SCHEMBL17594623 | 0.75 | KDM4E (0.40) | LMNAALDH1A1SLC6A4CHRM1CRBN | |
| Hydrochloric Acid SCHEMBL19585552 | 0.75 | CYP4A11 (0.55) | ITGB3ITGA2B | |
| SCHEMBL10360804 | 0.75 | ALDH1A1 (0.77) | LMNAALDH1A1SLC6A3HIF1ATSHR | |
| SCHEMBL11400538 | 0.75 | SLC6A4 (0.61) | SLC6A4NAMPTITGB3ITGA2B | |
| SCHEMBL1789262 | 0.74 | ALDH1A1 (0.66) | LMNAALDH1A1DHODHHIF1ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6265434-B1 | ANTIINFLAMMATORY AGENTS | MERCK & CO., INC. | 2001-07-24 | — | — | US | disclosed |