Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | PPM1D | O15297 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | CFTR | P13569 | 1/20 | 0.42 |
| ▸ | SCN1A | P35498 | 1/20 | 0.42 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.42 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23023052 | 0.82 | HIF1A (0.47) | ALDH1A1LMNAKDM4EHPGDHSD17B10 | |
| Hydrochloric Acid SCHEMBL23004994 | 0.81 | HIF1A (0.46) | ALDH1A1LMNAKDM4EHPGDHSD17B10 | |
| SCHEMBL24257656 | 0.81 | CA12 (0.48) | ALDH1A1KDM4EHPGDHSD17B10NPSR1 | |
| SCHEMBL21180886 | 0.81 | ABL1 (0.48) | ALDH1A1LMNAKDM4EHPGDHSD17B10 | |
| SCHEMBL10360804 | 0.81 | ALDH1A1 (0.77) | ALDH1A1LMNAKDM4EHSD17B10TSHR | |
| SCHEMBL30096071 | 0.80 | ALDH1A1 (0.48) | ALDH1A1LMNAKDM4EHPGDHSD17B10 | |
| SCHEMBL7987100 | 0.80 | LMNA (0.51) | ALDH1A1LMNATSHRHIF1ASCN1A | |
| SCHEMBL15626640 | 0.80 | PPM1D (0.44) | ALDH1A1KDM4EHPGDHSD17B10TSHR | |
| SCHEMBL19515023 | 0.80 | ALDH1A1 (0.55) | ALDH1A1LMNAKDM4EHPGDHSD17B10 | |
| SCHEMBL6175349 | 0.79 | TP53 (0.43) | ALDH1A1HPGDHSD17B10KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3221304-B1 | NOVEL CARBOXYLIC ACID COMPOUNDS USEFUL FOR INHIBITING MICROSOMAL PROSTAGLANDIN E2 SYNTHASE-1 | LILLY CO ELI (US) | 2019-07-24 | — | — | EP | disclosed |