Morpholine

Morpholine

SCHEMBL7987130

C1COCCN1.NC(N)=S

nearest known ligand 0.61

Full drug profile on Sugi Atlas →

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.61
KMT2A Q03164 1/20 0.61
KDM4E B2RXH2 1/20 0.61
GAA P10253 1/20 0.61
CYP2C9 P11712 1/20 0.61
SMN1; SMN2 Q16637 2/20 0.36
HTT P42858 1/20 0.36
TSHR P16473 1/20 0.35
ATM Q13315 1/20 0.35
ATR Q13535 1/20 0.35
LMNA P02545 1/20 0.35
APEX1 P27695 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Morpholine SCHEMBL702116 0.89 MEN1 (0.55) MEN1KMT2AKDM4EGAACYP2C9
Morpholine SCHEMBL497396 0.89 MEN1 (0.55) MEN1KMT2AKDM4EGAACYP2C9
Morpholine SCHEMBL10425540 0.87 MEN1 (0.52) MEN1KMT2AKDM4EGAACYP2C9
Morpholine SCHEMBL29191392 0.87 MEN1 (0.52) MEN1KMT2AKDM4EGAACYP2C9
Morpholine SCHEMBL8009459 0.84
Morpholine SCHEMBL2520893 0.82 KDM4E (0.61) MEN1KMT2AKDM4EGAACYP2C9
Morpholine SCHEMBL7554037 0.82 MEN1 (0.61) MEN1KMT2AKDM4EGAACYP2C9
Morpholine SCHEMBL8004690 0.81
Morpholine SCHEMBL28322795 0.81
Morpholine SCHEMBL7996463 0.80 MEN1 (0.92) MEN1KMT2AKDM4EGAACYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2867319-A1 ACCELERATORS FOR TWO STEP ADHESIVE SYSTEMS Henkel US IP LLC (US) 2015-05-06 EP disclosed
WO-2014004311-A1 ACCELERATORS FOR TWO STEP ADHESIVE SYSTEMS Henkel US IP LLC (US) 2014-01-03 WO disclosed
CN-102548976-A (Thio) morpholine derivatives as S1P modulators ABBOTT HEALTHCARE PRODUCTS BV 2012-07-04 CN disclosed
EP-0979208-A4 COMPOSITION AND METHOD FOR REDUCING COPPER OXIDE TO METALLIC COPPER MORTON INT INC (US) 2000-10-25 EP disclosed
EP-0979208-A1 COMPOSITION AND METHOD FOR REDUCING COPPER OXIDE TO METALLIC COPPER MORTON INTERNATIONAL, INC. (US) 2000-02-16 EP disclosed
EP-0938447-A1 COMPOSITION AND METHOD FOR REDUCING COPPER OXIDE TO METALLIC COPPER MORTON INTERNATIONAL, INC. (US) 1999-09-01 EP disclosed
EP-0938447-A4 1999-09-01 EP disclosed
WO-1999042402-A1 COMPOSITION AND METHOD FOR REDUCING COPPER OXIDE TO METALLIC COPPER MORTON INTERNATIONAL, INC. (US) 1999-08-26 WO disclosed
CN-1220645-A Composition and method for reducing copper oxide to metallic copper MORTON INT INC (US) 1999-06-23 CN disclosed
WO-1999002452-A1 COMPOSITION AND METHOD FOR REDUCING COPPER OXIDE TO METALLIC COPPER MORTON INTERNATIONAL, INC. (US) 1999-01-21 WO disclosed