Morpholine

Morpholine

SCHEMBL497396

C1COCCN1.NC(=S)S

nearest known ligand 0.55

Full drug profile on Sugi Atlas →

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.55
KMT2A Q03164 1/20 0.55
KDM4E B2RXH2 1/20 0.55
GAA P10253 1/20 0.55
CYP2C9 P11712 1/20 0.55
SMN1; SMN2 Q16637 2/20 0.33
HTT P42858 1/20 0.33
LMNA P02545 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Morpholine SCHEMBL7987130 0.89 MEN1 (0.61) MEN1KMT2AKDM4EGAACYP2C9
Morpholine SCHEMBL702116 0.84 MEN1 (0.55) MEN1KMT2AKDM4EGAACYP2C9
Aziridine SCHEMBL6276086 0.83 TSHR (0.36)
Aziridine SCHEMBL476461 0.83
Morpholine SCHEMBL10425540 0.82 MEN1 (0.52) MEN1KMT2AKDM4EGAACYP2C9
Morpholine SCHEMBL29191392 0.82 MEN1 (0.52) MEN1KMT2AKDM4EGAACYP2C9
Piperazine SCHEMBL989787 0.80 HIF1A (0.43) KDM4EGAACYP2C9SMN1; SMN2
Morpholine SCHEMBL8009459 0.80
Piperazine SCHEMBL3767537 0.80 HIF1A (0.43) KDM4EGAACYP2C9SMN1; SMN2
Dioxane SCHEMBL28136360 0.80 TTR (0.43) MEN1KMT2AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4294576-B1 DITHIOCARBAMATE DEPRESSANTS, METHODS AND USES THEREOF IN FROTH FLOTATION MINERAL SEPARATION TESSENDERLO KERLEY INC (US) 2024-12-25 EP claimed
US-20240149277-A1 DITHIOCARBAMATE DEPRESSANTS, METHODS AND USES THEREOF IN FROTH FLOTATION MINERAL SEPARATION TESSENDERLO KERLEY, INC. (US) 2024-05-09 US claimed
CN-113004333-A Bi-one-dimensional chain bismuth complex and preparation method thereof 吕梁学院 2021-06-22 CN claimed
EP-1986553-B1 U-SHAPED DISC-SHUNT AND DELIVERY DEVICE ALEEVA MEDICAL INC (US) 2016-03-30 EP claimed
CN-102977978-B Bearing lubricating grease and preparation method thereof WUXI EGOLS LUBRICATION TECHNOLOGY CO LTD 2015-06-24 CN claimed
CN-102977978-A Bearing lubricating grease and preparation method thereof WUXI EGOLS LUBRICATION TECHNOLOGY CO LTD 2013-03-20 CN claimed
US-8361007-B2 U-shaped disc shunt and delivery device ALEEVA MEDICAL INC. (US) 2013-01-29 US claimed
CN-101815811-A Be used for handling the composition and the method on copper surface EKC TECHNOLOGY INC 2010-08-25 CN claimed
EP-2191041-A1 COMPOSITIONS AND METHOD FOR TREATING A COPPER SURFACE EKC Technology, INC. (US) 2010-06-02 EP claimed
WO-2009032322-A1 COMPOSITIONS AND METHOD FOR TREATING A COPPER SURFACE EKC TECHNOLOGY, INC. (US) 2009-03-12 WO claimed
US-20090068846-A1 COMPOSITIONS AND METHOD FOR TREATING A COPPER SURFACE EKC TECHNOLOGY, INC. 2009-03-12 US claimed
US-20090024071-A1 U-Shaped Disc Shunt and Delivery Device YEUNG JEFFREY E 2009-01-22 US claimed
EP-1986553-A2 U-SHAPED DISC-SHUNT AND DELIVERY DEVICE Aleeva Medical, Inc. (US) 2008-11-05 EP claimed
WO-2007089947-A2 U-SHAPED DISC-SHUNT AND DELIVERY DEVICE ALEEVA MEDICAL INC. (US) 2007-08-09 WO claimed
US-20070169911-A1 U-shaped disc shunt and delivery device ALEEVA MEDICAL INC., A DELAWARE CORPORATION 2007-07-26 US claimed
US-20070142791-A1 U-shaped disc shunt and delivery device ALEEVE MEDICAL INC. A DELAWARE CORPORATION 2007-06-21 US claimed
EP-4294576-B1 DITHIOCARBAMATE DEPRESSANTS, METHODS AND USES THEREOF IN FROTH FLOTATION MINERAL SEPARATION TESSENDERLO KERLEY INC (US) 2024-12-25 EP disclosed
US-20240149277-A1 DITHIOCARBAMATE DEPRESSANTS, METHODS AND USES THEREOF IN FROTH FLOTATION MINERAL SEPARATION TESSENDERLO KERLEY, INC. (US) 2024-05-09 US disclosed
US-20070142791-A1 U-shaped disc shunt and delivery device ALEEVE MEDICAL INC. A DELAWARE CORPORATION 2007-06-21 US disclosed
JP-2006160769-A HEAVY METAL SCAVENGER CONTAINING MORPHOLINE DITHIOCARBAMIC ACID ALKALI METAL SALT NIHON HELS INDUSTRY CORP 2006-06-22 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240149277-A1 DITHIOCARBAMATE DEPRESSANTS, METHODS AND USES THEREOF IN FROTH FLOTATION MINERAL SEPARATION ACMSD, AP2A1, CA3 MEN1 3923/4885KMT2A 1760/4885KDM4E 2856/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.