Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | NAAA | Q02083 | 3/20 | 0.43 |
| ▸ | TLR2 | O60603 | 3/20 | 0.41 |
| ▸ | TLR1 | Q15399 | 3/20 | 0.41 |
| ▸ | KDM1A | O60341 | 10/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4384276 | 1.00 | SMN1; SMN2 (0.43) | SMN1; SMN2NPSR1NAAATLR2TLR1 | |
| SCHEMBL8398650 | 0.82 | NAAA (0.47) | SMN1; SMN2NAAA | |
| SCHEMBL8397460 | 0.82 | NAAA (0.47) | SMN1; SMN2NAAA | |
| SCHEMBL7961372 | 0.77 | NPC1 (0.62) | SMN1; SMN2NPSR1 | |
| SCHEMBL7977532 | 0.76 | SMN1; SMN2 (0.44) | SMN1; SMN2NPSR1NAAAHRH3 | |
| SCHEMBL7977480 | 0.75 | EPHX1 (0.51) | NAAAHRH3 | |
| SCHEMBL7974350 | 0.75 | NPC1 (0.46) | SMN1; SMN2HRH3 | |
| SCHEMBL7977081 | 0.74 | HRH3 (0.49) | SMN1; SMN2HDAC6HRH3 | |
| SCHEMBL4376053 | 0.74 | HRH3 (0.49) | SMN1; SMN2HRH3 | |
| SCHEMBL4376634 | 0.73 | NPC1 (0.47) | SMN1; SMN2HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6248765-B1 | ANTIINFLAMMATORY AGENTS; HYPOTENSIVE AGENTS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICAL (FR) | 2001-06-19 | — | — | US | claimed |