Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.47 |
| ▸ | HRH2 | P25021 | 1/20 | 0.46 |
| ▸ | HRH1 | P35367 | 1/20 | 0.46 |
| ▸ | LSS | P48449 | 2/20 | 0.45 |
| ▸ | PPARG | P37231 | 3/20 | 0.42 |
| ▸ | PPARA | Q07869 | 3/20 | 0.42 |
| ▸ | PPARD | Q03181 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.40 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.40 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7961327 | 0.89 | RAB9A (0.43) | HRH3LMNAALDH1A1 | |
| SCHEMBL7987181 | 0.88 | GAA (0.55) | HRH3PPARGPPARAPPARDLMNA | |
| SCHEMBL7974440 | 0.84 | GAA (0.56) | HRH3PPARGPPARALMNASMN1; SMN2 | |
| SCHEMBL4376187 | 0.83 | L3MBTL1 (0.59) | HRH3HRH2HRH1LMNASMN1; SMN2 | |
| SCHEMBL4379847 | 0.82 | HTR2A (0.42) | HRH3LMNASMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL7977335 | 0.81 | SMN1; SMN2 (0.51) | HRH3HRH2HRH1SMN1; SMN2GAA | |
| SCHEMBL4376108 | 0.80 | NPC1 (0.48) | HRH3HRH1SMN1; SMN2ALDH1A1NPSR1 | |
| SCHEMBL7988256 | 0.80 | HPGD (0.55) | HRH2HRH1LMNASMN1; SMN2KDM4E | |
| SCHEMBL4392013 | 0.80 | HRH3 (0.43) | HRH3GAA | |
| SCHEMBL8795425 | 0.79 | FFAR1 (0.39) | PPARGPPARALMNASMN1; SMN2FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6248765-B1 | ANTIINFLAMMATORY AGENTS; HYPOTENSIVE AGENTS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICAL (FR) | 2001-06-19 | — | — | US | claimed |
| US-6248765-B1 | ANTIINFLAMMATORY AGENTS; HYPOTENSIVE AGENTS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICAL (FR) | 2001-06-19 | — | — | US | disclosed |