Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | HRH3 | Q9Y5N1 | 7/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | HRH2 | P25021 | 1/20 | 0.46 |
| ▸ | HRH1 | P35367 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4381007 | 0.93 | SMN1; SMN2 (0.52) | SMN1; SMN2NPC1MAPTHPGDRAB9A | |
| SCHEMBL7987565 | 0.90 | L3MBTL1 (0.55) | SMN1; SMN2NPC1MAPTHRH3L3MBTL1 | |
| Oxalic Acid SCHEMBL7988348 | 0.90 | SMN1; SMN2 (0.49) | SMN1; SMN2NPC1MAPTHPGDRAB9A | |
| SCHEMBL7990745 | 0.88 | HRH2 (0.57) | L3MBTL1HRH2HRH1 | |
| SCHEMBL7987723 | 0.87 | HRH2 (0.56) | L3MBTL1HRH2HRH1 | |
| SCHEMBL4376187 | 0.86 | L3MBTL1 (0.59) | SMN1; SMN2MAPTHRH3GAAL3MBTL1 | |
| SCHEMBL7987591 | 0.86 | HRH3 (0.42) | MAPTHRH3L3MBTL1 | |
| SCHEMBL4383633 | 0.85 | KMT2A (0.45) | — | |
| SCHEMBL7994845 | 0.85 | L3MBTL1 (0.48) | NPC1MAPTHRH3L3MBTL1HRH2 | |
| SCHEMBL4392013 | 0.83 | HRH3 (0.43) | NPC1RAB9AHRH3GAAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6248765-B1 | ANTIINFLAMMATORY AGENTS; HYPOTENSIVE AGENTS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICAL (FR) | 2001-06-19 | — | — | US | claimed |