Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 4/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | CA7 | P43166 | 2/20 | 0.42 |
| ▸ | CA9 | Q16790 | 2/20 | 0.42 |
| ▸ | IDO1 | P14902 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 2/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | TDO2 | P48775 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.35 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7989311 | 0.99 | CA1 (0.44) | CA1CA2CA7CA9IDO1 | |
| SCHEMBL7987303 | 0.95 | HSP90AA1 (0.43) | CA1CA2CA7CA9IDO1 | |
| SCHEMBL7976011 | 0.94 | CA1 (0.45) | CA1CA2CA7CA9IDO1 | |
| SCHEMBL7447822 | 0.94 | HSP90AA1 (0.44) | CA1CA2CA7CA9IDO1 | |
| SCHEMBL7989824 | 0.92 | ALDH1A1 (0.39) | CA1CA2CA7CA9IDO1 | |
| SCHEMBL7987648 | 0.92 | HSP90AA1 (0.39) | CA1CA2CA7CA9IDO1 | |
| SCHEMBL7975758 | 0.91 | MAOB (0.48) | MAOBLPAR1LPAR5 | |
| SCHEMBL7989863 | 0.89 | IDO1 (0.36) | CA1CA2CA7CA9IDO1 | |
| SCHEMBL7986153 | 0.89 | LMNA (0.39) | IDO1KMT2AMEN1ALDH1A1MAOB | |
| SCHEMBL7506587 | 0.89 | HTR1A (0.43) | KMT2AMEN1TP53GAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6313177-B1 | AS ANTIVIRAL AGENTS | PHARMACOR INC. (CA) | 2001-11-06 | — | — | US | disclosed |