Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 1/20 | 0.42 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.42 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | CASP3 | P42574 | 2/20 | 0.39 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.39 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | FLT3 | P36888 | 1/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7775103 | 0.93 | AR (0.42) | ARLOXL2AOC3NPC1RAB9A | |
| SCHEMBL4273420 | 0.82 | MAPT (0.45) | ARLOXL2AOC3NPC1RAB9A | |
| SCHEMBL7207164 | 0.82 | LOXL2 (0.50) | ARLOXL2AOC3NPC1RAB9A | |
| SCHEMBL7331250 | 0.81 | AR (0.41) | ARLOXL2AOC3NPC1RAB9A | |
| SCHEMBL31370881 | 0.81 | KDM4E (0.41) | ARLOXL2AOC3NPC1RAB9A | |
| SCHEMBL5557187 | 0.81 | LOXL2 (0.49) | ARLOXL2AOC3NPC1RAB9A | |
| SCHEMBL4265909 | 0.81 | DRD2 (0.46) | ARLOXL2AOC3NPC1RAB9A | |
| SCHEMBL7084107 | 0.79 | GPR84 (0.45) | ARKDM4EMAPTALDH1A1MAPK1 | |
| SCHEMBL17646132 | 0.78 | PDGFRB (0.55) | KDM4EALDH1A1FLT3 | |
| SCHEMBL7166907 | 0.78 | CYP2A6 (0.46) | ARLOXL2AOC3NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6291683-B1 | AS ANTIDEPRESSANTS | AMERICAN HOME PRODUCTS CORP | 2001-09-18 | — | — | US | disclosed |