Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.34 |
| ▸ | HTR6 | P50406 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | MAPKAPK2 | P49137 | 2/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.32 |
| ▸ | BCHE | P06276 | 1/20 | 0.31 |
| ▸ | SCN3A | Q9NY46 | 3/20 | 0.31 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CKS1B | P61024 | 1/20 | 0.31 |
| ▸ | SKP1 | P63208 | 1/20 | 0.31 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.31 |
| ▸ | SREBF2 | Q12772 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7986647 | 0.92 | MEN1 (0.37) | L3MBTL1PDE10AHTR6FAAHMEN1 | |
| SCHEMBL7986418 | 0.91 | MEN1 (0.34) | L3MBTL1PDE10AHTR6FAAHMEN1 | |
| SCHEMBL7987559 | 0.89 | L3MBTL1 (0.36) | L3MBTL1PDE10AHTR6FAAHGPR119 | |
| SCHEMBL7994297 | 0.88 | GPR119 (0.35) | L3MBTL1PDE10AHTR6FAAHGPR119 | |
| SCHEMBL7975881 | 0.80 | MEN1 (0.35) | L3MBTL1PDE10AHTR6FAAHMEN1 | |
| SCHEMBL7990760 | 0.79 | L3MBTL1 (0.33) | L3MBTL1PDE10AHTR6FAAHGPR119 | |
| SCHEMBL7989594 | 0.76 | L3MBTL1 (0.36) | L3MBTL1HTR6FAAHGPR119MEN1 | |
| SCHEMBL8954140 | 0.74 | L3MBTL1 (0.42) | L3MBTL1FAAHMEN1POLBMAPT | |
| SCHEMBL28746043 | 0.73 | NR1H2 (0.35) | PDE10AHTR6FAAHGPR119MEN1 | |
| SCHEMBL7987345 | 0.71 | L3MBTL1 (0.33) | L3MBTL1PDE10AHTR6FAAHMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6207686-B1 | FOR THERAPY OF HYPERTENSION | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-03-27 | — | — | US | disclosed |
| WO-1996015109-A1 | ENDOTHELIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-05-23 | — | — | WO | disclosed |