Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.32 |
| ▸ | SCN3A | Q9NY46 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HTR6 | P50406 | 1/20 | 0.32 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.32 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.32 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.32 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.32 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7975881 | 0.96 | MEN1 (0.35) | L3MBTL1NR1H2PDE10AMEN1POLB | |
| SCHEMBL7994297 | 0.91 | GPR119 (0.35) | L3MBTL1NR1H2PDE10ASCN9ASCN3A | |
| SCHEMBL7986418 | 0.89 | MEN1 (0.34) | L3MBTL1NR1H2PDE10AMEN1POLB | |
| SCHEMBL7989594 | 0.85 | L3MBTL1 (0.36) | L3MBTL1NR1H2MEN1KMT2ASCN9A | |
| SCHEMBL7986647 | 0.85 | MEN1 (0.37) | L3MBTL1NR1H2PDE10AMEN1POLB | |
| SCHEMBL8954140 | 0.80 | L3MBTL1 (0.42) | L3MBTL1MEN1POLBMAPTKMT2A | |
| SCHEMBL7987489 | 0.79 | L3MBTL1 (0.34) | L3MBTL1NR1H2PDE10AMEN1POLB | |
| SCHEMBL7987345 | 0.77 | L3MBTL1 (0.33) | L3MBTL1PDE10AMEN1POLBMAPT | |
| SCHEMBL12821621 | 0.77 | SCN3A (0.41) | MEN1POLBMAPTKMT2ASCN9A | |
| SCHEMBL28746043 | 0.76 | NR1H2 (0.35) | NR1H2PDE10AMEN1KMT2ASCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6207686-B1 | FOR THERAPY OF HYPERTENSION | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-03-27 | — | — | US | disclosed |
| WO-1996015109-A1 | ENDOTHELIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-05-23 | — | — | WO | disclosed |