Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 15/20 | 0.50 |
| ▸ | DRD3 | P35462 | 6/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.50 |
| ▸ | FAAH | O00519 | 1/20 | 0.49 |
| ▸ | CNR1 | P21554 | 1/20 | 0.49 |
| ▸ | HTR7 | P34969 | 10/20 | 0.48 |
| ▸ | HTR6 | P50406 | 10/20 | 0.48 |
| ▸ | HTR2A | P28223 | 9/20 | 0.48 |
| ▸ | HTR1A | P08908 | 7/20 | 0.48 |
| ▸ | DRD4 | P21917 | 2/20 | 0.47 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.47 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL797823 | 0.87 | DRD2 (0.50) | DRD2DRD3ADRA1AFAAHHTR7 | |
| SCHEMBL798019 | 0.84 | DRD2 (0.48) | DRD2DRD3ADRA1AFAAHHTR7 | |
| SCHEMBL792805 | 0.83 | DRD2 (0.53) | DRD2DRD3ADRA1AFAAHCNR1 | |
| SCHEMBL792808 | 0.82 | DRD2 (0.62) | DRD2DRD3ADRA1AHTR7HTR6 | |
| SCHEMBL798604 | 0.82 | HTR7 (0.57) | DRD2DRD3ADRA1AFAAHCNR1 | |
| SCHEMBL791263 | 0.82 | DRD2 (0.58) | DRD2DRD3ADRA1AFAAHCNR1 | |
| SCHEMBL792676 | 0.81 | DRD2 (0.64) | DRD2DRD3ADRA1AFAAHCNR1 | |
| SCHEMBL798862 | 0.81 | HTR1A (0.51) | DRD2DRD3FAAHCNR1HTR7 | |
| SCHEMBL792428 | 0.81 | HTR7 (0.56) | DRD2DRD3ADRA1AFAAHCNR1 | |
| SCHEMBL792464 | 0.79 | HTR7 (0.63) | DRD2DRD3ADRA1AFAAHCNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2616440-A1 | ARYLOSULFONAMIDES FOR THE TREATMENT OF CNS DISEASES | Adamed sp. z o.o. (PL) | 2013-07-24 | — | — | EP | claimed |
| WO-2012035123-A1 | ARYLOSULFONAMIDES FOR THE TREATMENT OF CNS DISEASES | ADAMED SP. Z O.O. (PL) | 2012-03-22 | — | — | WO | claimed |