Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.67 |
| ▸ | HPGD | P15428 | 3/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.64 |
| ▸ | HTT | P42858 | 2/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.62 |
| ▸ | LMNA | P02545 | 3/20 | 0.62 |
| ▸ | GAA | P10253 | 3/20 | 0.62 |
| ▸ | TP53 | P04637 | 1/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.59 |
| ▸ | USP2 | O75604 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | ATM | Q13315 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL806760 | 0.89 | SMN1; SMN2 (0.75) | MAPTHPGDHTTSMN1; SMN2LMNA | |
| SCHEMBL17340105 | 0.86 | SMN1; SMN2 (0.68) | MAPTHPGDALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL806438 | 0.85 | SMN1; SMN2 (0.83) | MAPTHPGDALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL798403 | 0.84 | OXTR (0.69) | MAPTHPGDHTTSMN1; SMN2LMNA | |
| SCHEMBL15583931 | 0.82 | MAPT (0.75) | MAPTHPGDTSHR | |
| SCHEMBL18101489 | 0.81 | SMN1; SMN2 (0.70) | MAPTHPGDALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL1629150 | 0.80 | KEAP1 (0.77) | — | |
| SCHEMBL16557468 | 0.78 | HPGD (0.81) | MAPTHPGDALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL16557596 | 0.78 | MAPT (0.69) | MAPTHPGDTP53 | |
| SCHEMBL16557554 | 0.78 | MAPT (0.72) | MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9212134-B2 | Inhibitors of viral entry into mammalian cells | MICROBIOTIX, INC. (US) | 2015-12-15 | — | — | US | disclosed |
| CN-103491956-A | Inhibitors of viral entry into mammalian cells | MICROBIOTIX INC | 2014-01-01 | — | — | CN | disclosed |
| EP-2616073-A2 | INHIBITORS OF VIRAL ENTRY INTO MAMMALIAN CELLS | Microbiotix, Inc. (US) | 2013-07-24 | — | — | EP | disclosed |
| WO-2012037119-A2 | INHIBITORS OF VIRAL ENTRY INTO MAMMALIAN CELLS | MICROBIOTIX, INC. (US) | 2012-03-22 | — | — | WO | disclosed |
| WO-2012037119-A2 | INHIBITORS OF VIRAL ENTRY INTO MAMMALIAN CELLS | MICROBIOTIX, INC. (US) | 2012-03-22 | — | — | WO | disclosed |