Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.83 |
| ▸ | HPGD | P15428 | 1/20 | 0.68 |
| ▸ | ATM | Q13315 | 1/20 | 0.68 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.68 |
| ▸ | LMNA | P02545 | 2/20 | 0.67 |
| ▸ | GAA | P10253 | 1/20 | 0.67 |
| ▸ | OXTR | P30559 | 3/20 | 0.66 |
| ▸ | AVPR1A | P37288 | 2/20 | 0.66 |
| ▸ | MEN1 | O00255 | 2/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.65 |
| ▸ | MAPT | P10636 | 3/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL806760 | 0.96 | SMN1; SMN2 (0.75) | SMN1; SMN2HPGDATML3MBTL1LMNA | |
| SCHEMBL798403 | 0.91 | OXTR (0.69) | SMN1; SMN2HPGDATML3MBTL1LMNA | |
| SCHEMBL17340105 | 0.91 | SMN1; SMN2 (0.68) | SMN1; SMN2HPGDATML3MBTL1LMNA | |
| SCHEMBL806780 | 0.91 | SMN1; SMN2 (1.00) | SMN1; SMN2HPGDATML3MBTL1LMNA | |
| SCHEMBL10053396 | 0.88 | SMN1; SMN2 (0.86) | SMN1; SMN2HPGDATML3MBTL1LMNA | |
| SCHEMBL798762 | 0.85 | MAPT (0.67) | SMN1; SMN2HPGDATML3MBTL1LMNA | |
| SCHEMBL17340103 | 0.85 | TP53 (0.74) | SMN1; SMN2LMNAOXTRAVPR1AMEN1 | |
| SCHEMBL806651 | 0.84 | OXTR (0.66) | SMN1; SMN2OXTRAVPR1AMEN1KMT2A | |
| SCHEMBL3366701 | 0.82 | OXTR (0.82) | SMN1; SMN2LMNAOXTRAVPR1AMEN1 | |
| SCHEMBL18963016 | 0.81 | MAPT (0.79) | SMN1; SMN2OXTRAVPR1AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9212134-B2 | Inhibitors of viral entry into mammalian cells | MICROBIOTIX, INC. (US) | 2015-12-15 | — | — | US | disclosed |
| WO-2012037119-A2 | INHIBITORS OF VIRAL ENTRY INTO MAMMALIAN CELLS | MICROBIOTIX, INC. (US) | 2012-03-22 | — | — | WO | disclosed |