Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | HTR7 | P34969 | 3/20 | 0.40 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.39 |
| ▸ | HTR1B | P28222 | 3/20 | 0.38 |
| ▸ | HTR1D | P28221 | 2/20 | 0.38 |
| ▸ | MAPK8 | P45983 | 4/20 | 0.37 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.36 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.36 |
| ▸ | CCR4 | P51679 | 1/20 | 0.35 |
| ▸ | FLT3 | P36888 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12501346 | 0.84 | HRH3 (0.44) | HRH3CHRNB2CHRNA4HTR1BHTR1D | |
| SCHEMBL26573670 | 0.77 | FLT3 (0.39) | MAPK8FLT3LMNA | |
| SCHEMBL14422893 | 0.70 | HTR1B (0.52) | HRH3CHRNB2CHRNA4HTR1BHTR1D | |
| SCHEMBL19265688 | 0.70 | RXRA (0.41) | HRH3CHRNB2CHRNA4HTR1BHTR1D | |
| SCHEMBL4537708 | 0.70 | FDPS (0.44) | HTR7MAPK8FLT3 | |
| SCHEMBL2844731 | 0.68 | ABL1 (0.52) | HTR7MAPK8ADRA1DADRA1AADRA1B | |
| SCHEMBL15357779 | 0.68 | FLT3 (0.41) | MAPK8FLT3 | |
| SCHEMBL10212545 | 0.66 | HRH4 (0.55) | HRH3 | |
| SCHEMBL12356602 | 0.66 | FLT3 (0.40) | HTR7MAPK8FLT3 | |
| SCHEMBL1774897 | 0.66 | GAA (0.42) | MAPK8FLT3TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009143156-A2 | IMIDAZO[1,2-a]PYRIDINE COMPOUNDS | SEPRACOR INC. (US) | 2009-11-26 | — | — | WO | disclosed |