Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCD | O00767 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.46 |
| ▸ | ACP1 | P24666 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.44 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | XBP1 | P17861 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7987690 | 0.87 | PKM (0.43) | TSHRCYP11B1CYP11B2HTTSMN1; SMN2 | |
| SCHEMBL16076196 | 0.87 | SCD (0.49) | SCDTSHRACP1MAPK1CYP11B1 | |
| SCHEMBL7988530 | 0.87 | SMN1; SMN2 (0.46) | SCDTSHRCYP11B1CYP11B2HTT | |
| SCHEMBL5483136 | 0.86 | PKM (0.59) | TSHRADRA1DACP1CYP11B1CYP11B2 | |
| SCHEMBL18050890 | 0.85 | SCD (0.56) | SCDTSHRADRA1DACP1MAPK1 | |
| Hydrochloric Acid SCHEMBL7987445 | 0.85 | PKM (0.57) | TSHRADRA1DACP1CYP11B1CYP11B2 | |
| SCHEMBL2145728 | 0.85 | SCD (0.50) | SCDTSHRADRA1DACP1MAPK1 | |
| SCHEMBL7974026 | 0.85 | KDM4E (0.58) | TSHRADRA1DACP1MAPK1CYP11B1 | |
| SCHEMBL7984484 | 0.84 | PKM (0.50) | TSHRADRA1DCYP11B1CYP11B2HTT | |
| Hydrochloric Acid SCHEMBL7991220 | 0.84 | PKM (0.42) | SCDTSHRMAPK1CYP11B1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |