Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.42 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | QPCT | Q16769 | 2/20 | 0.39 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.39 |
| ▸ | MET | P08581 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7987743 | 0.87 | SCD (0.50) | PKMGAATSHRCYP11B2HTT | |
| SCHEMBL2145385 | 0.85 | PKM (0.43) | PKMGAATSHRMAPK14CYP11B2 | |
| SCHEMBL7988530 | 0.85 | SMN1; SMN2 (0.46) | PKMGAATSHRCYP11B2HTT | |
| SCHEMBL18050897 | 0.85 | PKM (0.49) | PKMGAATSHRMAPK14CYP11B2 | |
| SCHEMBL5483136 | 0.85 | PKM (0.59) | PKMGAATSHRCYP11B2CYP11B1 | |
| SCHEMBL7991370 | 0.85 | KDM4E (0.51) | PKMGAATSHRSMN1; SMN2QPCT | |
| Hydrochloric Acid SCHEMBL7987445 | 0.84 | PKM (0.57) | PKMGAATSHRCYP11B2CYP11B1 | |
| SCHEMBL7974168 | 0.83 | CDK9 (0.45) | PKMGAATSHRMAPK14CYP11B2 | |
| SCHEMBL7984484 | 0.83 | PKM (0.50) | PKMGAATSHRCYP11B2HTT | |
| Hydrochloric Acid SCHEMBL7991220 | 0.82 | PKM (0.42) | PKMGAATSHRCYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |