Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.52 |
| ▸ | ACP1 | P24666 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | UBE2N | P61088 | 1/20 | 0.46 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.46 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.45 |
| ▸ | FSCN1 | Q16658 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | YTHDC1 | Q96MU7 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18050886 | 0.87 | KDM4E (0.58) | KDM4EADRA1DACP1SMN1; SMN2L3MBTL1 | |
| SCHEMBL5483136 | 0.86 | PKM (0.59) | ADRA1DACP1EGLN1GAAPKM | |
| SCHEMBL7987743 | 0.85 | SCD (0.50) | ADRA1DACP1SMN1; SMN2HTTGAA | |
| Hydrochloric Acid SCHEMBL7987445 | 0.85 | PKM (0.57) | ADRA1DACP1EGLN1GAAPKM | |
| SCHEMBL7975372 | 0.84 | ALDH1A1 (0.51) | ADRA1DSMN1; SMN2HTTKMT2AGAA | |
| SCHEMBL7974168 | 0.84 | CDK9 (0.45) | SMN1; SMN2L3MBTL1GAAPKMTSHR | |
| SCHEMBL7984239 | 0.81 | ADRA1D (0.52) | ADRA1DKMT2AYTHDC1ADORA2AADORA1 | |
| SCHEMBL7974034 | 0.81 | ATM (0.48) | KDM4ESMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL7988093 | 0.81 | FYN (0.43) | KDM4EL3MBTL1KMT2AGAAPKM | |
| SCHEMBL28016885 | 0.80 | ACP1 (0.53) | KDM4EACP1SMN1; SMN2L3MBTL1GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |