Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNE2 | O96020 | 1/20 | 0.66 |
| ▸ | CDK4 | P11802 | 1/20 | 0.66 |
| ▸ | CCND1 | P24385 | 1/20 | 0.66 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.66 |
| ▸ | CDK2 | P24941 | 1/20 | 0.66 |
| ▸ | PRKCB | P05771 | 4/20 | 0.63 |
| ▸ | PRKCA | P17252 | 4/20 | 0.63 |
| ▸ | PRKCE | Q02156 | 3/20 | 0.63 |
| ▸ | PRKCD | Q05655 | 3/20 | 0.63 |
| ▸ | PRKCH | P24723 | 2/20 | 0.63 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.63 |
| ▸ | GSK3B | P49841 | 3/20 | 0.61 |
| ▸ | PRKCG | P05129 | 2/20 | 0.61 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.61 |
| ▸ | CAMK2B | Q13554 | 1/20 | 0.61 |
| ▸ | CAMK2G | Q13555 | 1/20 | 0.61 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.61 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.61 |
| ▸ | JAK3 | P52333 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7976776 | 0.92 | CDK4 (0.67) | CCNE2CDK4CCND1CCNE1CDK2 | |
| SCHEMBL7987101 | 0.91 | CDK4 (0.66) | CCNE2CDK4CCND1CCNE1CDK2 | |
| SCHEMBL3547465 | 0.89 | CDK4 (0.60) | CCNE2CDK4CCND1CCNE1CDK2 | |
| SCHEMBL7530443 | 0.89 | GSK3B (0.72) | CCNE2CDK4CCND1CCNE1CDK2 | |
| SCHEMBL990030 | 0.83 | GSK3B (0.62) | CCNE2CDK4CCND1CCNE1CDK2 | |
| SCHEMBL13038942 | 0.82 | CCNE2 (0.57) | CCNE2CDK4CCND1CCNE1CDK2 | |
| SCHEMBL4543351 | 0.82 | PRKCB (0.69) | CCNE2CDK4CCND1CCNE1CDK2 | |
| SCHEMBL30319849 | 0.81 | CCNE2 (1.00) | CCNE2CDK4CCND1CCNE1CDK2 | |
| SCHEMBL5686048 | 0.81 | CCNE2 (1.00) | CCNE2CDK4CCND1CCNE1CDK2 | |
| SCHEMBL7597574 | 0.81 | CCNE2 (0.69) | CCNE2CDK4CCND1CCNE1CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6281356-B1 | ANTICANRCER AGENTS | HOFFMANN-LA ROCHE INC. | 2001-08-28 | — | — | US | claimed |
| US-6281356-B1 | ANTICANRCER AGENTS | HOFFMANN-LA ROCHE INC. | 2001-08-28 | — | — | US | disclosed |