Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7987131 | 0.88 | HTR7 (0.44) | HTR7POLBGAAKMT2APAX8 | |
| SCHEMBL7973489 | 0.83 | KDM4E (0.41) | POLBGAAKMT2AALDH1A1HDAC3 | |
| SCHEMBL7973249 | 0.83 | ALDH1A1 (0.47) | GAAKMT2AALDH1A1MAPTNPC1 | |
| SCHEMBL7973224 | 0.83 | HTT (0.42) | POLBKMT2AALDH1A1HDAC3HDAC1 | |
| SCHEMBL7973495 | 0.83 | NPSR1 (0.46) | GAAALDH1A1HPGDCES2CES1 | |
| SCHEMBL7983792 | 0.81 | CES2 (0.46) | POLBGAAKMT2AALDH1A1HPGD | |
| SCHEMBL7983580 | 0.81 | HDAC1 (0.43) | POLBKMT2AALDH1A1HDAC3HDAC1 | |
| SCHEMBL7983696 | 0.81 | CES2 (0.46) | HDAC3HDAC1HDAC2CES2CES1 | |
| SCHEMBL7987821 | 0.81 | USP5 (0.41) | POLBKMT2AALDH1A1HPGDMAPT | |
| SCHEMBL7984806 | 0.80 | PARP10 (0.50) | KMT2APAX8ALDH1A1HPGDNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6331628-B1 | REACTING A SUBSTITUTED HALOBENZENE WITH POTASSIUM, SODIUM AND/OR ZINC CYANIDE IN THE PRESENCE OF A METALLIC CATALYST | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2001-12-18 | — | — | US | disclosed |