Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 13/20 | 0.39 |
| ▸ | F10 | P00742 | 1/20 | 0.37 |
| ▸ | PLG | P00747 | 1/20 | 0.37 |
| ▸ | PLAT | P00750 | 1/20 | 0.37 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.37 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.37 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.37 |
| ▸ | NAMPT | P43490 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.30 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
| ▸ | PPIB | P23284 | 1/20 | 0.30 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7973611 | 0.87 | NAMPT (0.37) | NAMPT | |
| SCHEMBL8722553 | 0.84 | — | — | |
| SCHEMBL7987041 | 0.81 | NAMPT (0.37) | F2F10PLGPLATPRSS1 | |
| SCHEMBL7049735 | 0.81 | F2 (0.40) | F2F10PLGPLATPRSS1 | |
| SCHEMBL7049734 | 0.77 | NAMPT (0.37) | F2F10PLGPLATPRSS1 | |
| Hydrochloric Acid SCHEMBL8721658 | 0.76 | F2 (0.40) | F2F10PLGPLATPRSS1 | |
| SCHEMBL7991189 | 0.75 | F2 (0.44) | F2F10PLGPLATPRSS1 | |
| SCHEMBL7047178 | 0.75 | F2 (0.48) | F2F10PLGPLATPRSS1 | |
| SCHEMBL8725900 | 0.74 | F2 (0.31) | F2 | |
| Hydrochloric Acid SCHEMBL8933094 | 0.73 | F2 (0.38) | F2F10PLGPLATPRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6204385-B1 | REACTING THE CORRESPONDING NITRILE WITH AMMONIA, AMINE OR HYDRAZINE IN THE PRESENCE OF A MERCAPTOCARBOXYLIC ACID | BASF AKTIENGESELLSCHAFT (DE) | 2001-03-20 | — | — | US | disclosed |
| EP-0931069-B1 | PROCESS FOR PREPARING AMIDINES | BASF AG (DE) | 2000-11-29 | — | — | EP | disclosed |
| EP-0931069-A1 | PROCESS FOR PREPARING AMIDINES | BASF AKTIENGESELLSCHAFT (DE) | 1999-07-28 | — | — | EP | disclosed |
| WO-1998009950-A1 | PROCESS FOR PREPARING AMIDINES | BASF AKTIENGESELLSCHAFT (DE) | 1998-03-12 | — | — | WO | disclosed |