Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 1/20 | 0.37 |
| ▸ | F2 | P00734 | 11/20 | 0.36 |
| ▸ | F10 | P00742 | 1/20 | 0.33 |
| ▸ | PLG | P00747 | 1/20 | 0.33 |
| ▸ | PLAT | P00750 | 1/20 | 0.33 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.33 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.33 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | PPIB | P23284 | 1/20 | 0.32 |
| ▸ | MC4R | P32245 | 1/20 | 0.32 |
| ▸ | MC5R | P33032 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7049734 | 0.90 | NAMPT (0.37) | NAMPTF2F10PLGPLAT | |
| SCHEMBL7987916 | 0.81 | F2 (0.39) | NAMPTF2F10PLGPLAT | |
| SCHEMBL7989105 | 0.78 | NAMPT (0.39) | NAMPTMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL7049735 | 0.78 | F2 (0.40) | NAMPTF2F10PLGPLAT | |
| SCHEMBL7705663 | 0.73 | OPRM1 (0.32) | F2MEN1KMT2AALDH1A1 | |
| SCHEMBL7045869 | 0.73 | NAMPT (0.40) | NAMPTPPIB | |
| SCHEMBL8809674 | 0.73 | NAMPT (0.37) | NAMPTF2F10PLGPLAT | |
| SCHEMBL7973611 | 0.72 | NAMPT (0.37) | NAMPTMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL7991189 | 0.72 | F2 (0.44) | F2F10PLGPLATPRSS1 | |
| Acetic Acid SCHEMBL6477043 | 0.71 | NPC1L1 (0.32) | F2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6204385-B1 | REACTING THE CORRESPONDING NITRILE WITH AMMONIA, AMINE OR HYDRAZINE IN THE PRESENCE OF A MERCAPTOCARBOXYLIC ACID | BASF AKTIENGESELLSCHAFT (DE) | 2001-03-20 | — | — | US | disclosed |
| EP-0931069-B1 | PROCESS FOR PREPARING AMIDINES | BASF AG (DE) | 2000-11-29 | — | — | EP | disclosed |
| EP-1030840-A1 | CYCLIC AMINE DERIVATIVES AND THEIR USE AS DRUGS | TEIJIN LIMITED (JP) | 2000-08-30 | — | — | EP | disclosed |
| EP-0931069-A1 | PROCESS FOR PREPARING AMIDINES | BASF AKTIENGESELLSCHAFT (DE) | 1999-07-28 | — | — | EP | disclosed |
| WO-1999025686-A1 | CYCLIC AMINE DERIVATIVES AND THEIR USE AS DRUGS | TEIJIN LIMITED (JP) | 1999-05-27 | — | — | WO | disclosed |
| WO-1998009950-A1 | PROCESS FOR PREPARING AMIDINES | BASF AKTIENGESELLSCHAFT (DE) | 1998-03-12 | — | — | WO | disclosed |