Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.38 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.38 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.38 |
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.37 |
| ▸ | ROCK1 | Q13464 | 6/20 | 0.37 |
| ▸ | ROCK2 | O75116 | 6/20 | 0.37 |
| ▸ | MTOR | P42345 | 1/20 | 0.37 |
| ▸ | AURKA | O14965 | 1/20 | 0.37 |
| ▸ | PRKCB | P05771 | 1/20 | 0.37 |
| ▸ | GRK2 | P25098 | 1/20 | 0.37 |
| ▸ | AKT1 | P31749 | 1/20 | 0.37 |
| ▸ | GRK5 | P34947 | 1/20 | 0.37 |
| ▸ | GRK6 | P43250 | 1/20 | 0.37 |
| ▸ | CAMK2B | Q13554 | 1/20 | 0.37 |
| ▸ | RPS6KA1 | Q15418 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7988124 | 0.89 | SMN1; SMN2 (0.41) | CACNA1GCACNA1BCACNA1CYTHDC1HTR2C | |
| SCHEMBL7985460 | 0.89 | CNOT7 (0.45) | CACNA1GCACNA1BCACNA1CHTR2CSLC6A4 | |
| SCHEMBL7988933 | 0.87 | GAA (0.44) | TP53RXFP1GAACACNA1GCACNA1B | |
| SCHEMBL7987945 | 0.84 | CACNA1G (0.39) | CACNA1GCACNA1BCACNA1CHTR2CSLC6A4 | |
| SCHEMBL7974301 | 0.84 | CACNA1G (0.40) | CACNA1GCACNA1BCACNA1CHTR2CSLC6A4 | |
| SCHEMBL7992288 | 0.84 | ABCC8 (0.41) | CACNA1GCACNA1BCACNA1CHTR2CSLC6A4 | |
| SCHEMBL7991608 | 0.82 | CNOT7 (0.47) | CACNA1GCACNA1BCACNA1CP2RX3HTR2C | |
| SCHEMBL7975225 | 0.81 | CACNA1G (0.40) | TP53CACNA1GCACNA1BCACNA1CP2RX3 | |
| SCHEMBL7984516 | 0.81 | TP53 (0.53) | TP53RXFP1GAAYTHDC1MAPT | |
| SCHEMBL7985316 | 0.80 | CNOT7 (0.48) | CACNA1GCACNA1BCACNA1CP2RX3HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |