Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARN | O95453 | 1/20 | 0.37 |
| ▸ | CNOT7 | Q9UIV1 | 1/20 | 0.37 |
| ▸ | AGTR1 | P30556 | 5/20 | 0.35 |
| ▸ | AGTR2 | P50052 | 5/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7987958 | 0.85 | SMN1; SMN2 (0.43) | AGTR1AGTR2ALDH1A1SMN1; SMN2 | |
| SCHEMBL7973938 | 0.82 | CNOT7 (0.48) | PARNCNOT7ALDH1A1SMN1; SMN2 | |
| SCHEMBL9708858 | 0.82 | CNOT7 (0.40) | PARNCNOT7AGTR1AGTR2ALDH1A1 | |
| SCHEMBL7975254 | 0.80 | CNOT7 (0.55) | PARNCNOT7ALDH1A1SMN1; SMN2 | |
| SCHEMBL7987439 | 0.77 | CNOT7 (0.43) | PARNCNOT7ALDH1A1SMN1; SMN2 | |
| SCHEMBL9707787 | 0.76 | CNOT7 (0.46) | PARNCNOT7AGTR1AGTR2ALDH1A1 | |
| SCHEMBL7984530 | 0.76 | HPGD (0.46) | PARNCNOT7ALDH1A1SMN1; SMN2 | |
| SCHEMBL7988132 | 0.76 | CNOT7 (0.44) | PARNCNOT7ALDH1A1SMN1; SMN2 | |
| SCHEMBL8813188 | 0.76 | AGTR1 (0.36) | AGTR1 | |
| SCHEMBL7985654 | 0.75 | CNOT7 (0.42) | PARNCNOT7ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |